Why is reversed filtration considered important in dialysis?

Reversed filtration plays a crucial role in dialysis because it addresses the concern of endotoxins, which are toxins released by bacteria. In high-flux hemodialysis, there is a risk that these endotoxins could cross the dialysis membrane and enter the bloodstream, potentially leading to serious health complications for the patient.

By implementing reversed filtration, the process helps to ensure that any substances, including harmful endotoxins, are effectively removed and not allowed to circulate back into the patient's system. This function is vital for maintaining patient safety and minimizing the risk of adverse reactions during treatment. Hence, option C correctly highlights the significance of reversed filtration in preventing endotoxin transfer during dialysis procedures.

The other options, while they mention valid concerns related to dialysis, do not directly relate to the specific function of reversed filtration in preventing endotoxin transfer. For instance, anaphylaxis and pyrogen reactions are serious but address different mechanisms and issues not directly linked to the role of reversed filtration. The concern about bicarbonate concentrate relates more to bacterial growth, which, while important, does not specifically pertain to the mechanism of reversed filtration in the context described.