What conditions increase susceptibility to infection in dialysis patients?

Diabetes mellitus significantly increases susceptibility to infection in dialysis patients due to several physiological factors. Individuals with diabetes often have a compromised immune response, making it more challenging for their bodies to fight off infections. This impaired immunity can be attributed to hyperglycemia, which affects white blood cell function, reducing their effectiveness in combating pathogens.

Additionally, dialysis patients, particularly those with diabetes, may experience skin and vascular complications that increase the risk of infections. The presence of diabetes also often leads to comorbid conditions that can further strain the immune system, making infections more likely.

While malnutrition, bone abnormalities, and frequent invasive procedures can influence infection risk as well, diabetes's profound impact on immune response is a primary reason for the heightened susceptibility observed in these patients. Therefore, understanding these connections can help healthcare providers implement targeted strategies to minimize infection risk in dialysis patients.